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  • Your Good Partner in Biology Research

    ITGB7

    Integrin beta-7 is a protein in humans that is encoded by ITGB7 gene. Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.

    ITGB7 Antibodies

    ITGB7 for Homo sapiens (Human)

    ITGB7 Proteins

    ITGB7 Proteins for Mus musculus (Mouse)

    ITGB7 Proteins for Homo sapiens (Human)

    ITGB7 ELISA Kit

    ITGB7 ELISA Kit for Homo sapiens (Human)



    1v1周青梅郑宣木天寥
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