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  • Your Good Partner in Biology Research

    IKBKB

    Inhibitor of nuclear factor kappa-B kinase subunit beta is a protein in humans that is encoded by IKBKB gene. Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis.

    IKBKB Antibodies

    IKBKB for Homo sapiens (Human)

    IKBKB Proteins

    IKBKB Proteins for Homo sapiens (Human)

    IKBKB Proteins for Mus musculus (Mouse)

    IKBKB Proteins for Bos taurus (Bovine)

    IKBKB Proteins for Rattus norvegicus (Rat)



    1v1周青梅郑宣木天寥
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