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  • Your Good Partner in Biology Research

    CRTC2

    CREB-regulated transcription coactivator 2 is a protein in humans that is encoded by CRTC2 gene. Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

    CRTC2 Antibodies

    CRTC2 for Homo sapiens (Human)

    CRTC2 Proteins

    CRTC2 Proteins for Mus musculus (Mouse)

    CRTC2 Proteins for Rattus norvegicus (Rat)

    CRTC2 Proteins for Homo sapiens (Human)



    1v1周青梅郑宣木天寥
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