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  • Your Good Partner in Biology Research

    CREB3L2

    Cyclic AMP-responsive element-binding protein 3-like protein 2 is a protein in humans that is encoded by CREB3L2 gene. Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes (By similarity).

    CREB3L2 Antibodies

    CREB3L2 for Homo sapiens (Human)

    CREB3L2 Proteins

    CREB3L2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

    CREB3L2 Proteins for Xenopus laevis (African clawed frog)

    CREB3L2 Proteins for Pongo abelii (Sumatran orangutan)

    CREB3L2 Proteins for Rattus norvegicus (Rat)

    CREB3L2 Proteins for Homo sapiens (Human)

    CREB3L2 Proteins for Mus musculus (Mouse)



    1v1周青梅郑宣木天寥
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