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  • Your Good Partner in Biology Research

    Recombinant Rat Muellerian-inhibiting factor(Amh) ,partial

    • 货号:
      CSB-YP001666RA
    • 规格:
    • 来源:
      Yeast
    • 其他:
    • 货号:
      CSB-EP001666RA
    • 规格:
    • 来源:
      E.coli
    • 其他:
    • 货号:
      CSB-EP001666RA-B
    • 规格:
    • 来源:
      E.coli
    • 共轭:
      Avi-tag Biotinylated

      E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

    • 其他:
    • 货号:
      CSB-BP001666RA
    • 规格:
    • 来源:
      Baculovirus
    • 其他:
    • 货号:
      CSB-MP001666RA
    • 规格:
    • 来源:
      Mammalian cell
    • 其他:

    产品详情

    • 纯度:
      >85% (SDS-PAGE)
    • 基因名:
      Amh
    • Uniprot No.:
    • 别名:
      Amh; Muellerian-inhibiting factor; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance; MIS
    • 种属:
      Rattus norvegicus (Rat)
    • 蛋白长度:
      Partial
    • 表达区域:
      -
    • 蛋白标签:
      The following tags are available.
      N-terminal His-tagged
      Tag-Free
      The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
    • 产品提供形式:
      Lyophilized powder
      Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
    • 复溶:
      We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
    • 储存条件:
      Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
    • 保质期:
      The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
      Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
    • 货期:
      Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
      Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
    • 注意事项:
      Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
    • Datasheet :
      Please contact us to get it.

    产品评价

    靶点详情

    • 功能:
      This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.
    • 基因功能参考文献:
      1. The study uncovers a new role for AMH in regulating gonadotrope function and suggests that AMH participates in the postnatal elevation of FSH secretion in females. PMID: 27030385
      2. AMH increases GnRH-dependent LH pulsatility and secretion, supporting a central action of AMH on GnRH neurons. PMID: 26753790
      3. Resveratrol reduced antimullerian hormone levels in rat model of polycystic ovary syndrome. PMID: 25667201
      4. AMH is the first hormone/protein shown to have an inhibitory action on primordial follicle assembly. PMID: 21637711
      5. In ovaries from adult cycling rats AMH protein is localized in large primary and secondary follicles and not in primordial or small primary follicles, with its highest expression in the largest preantral follicles. PMID: 20816688
      6. Mullerian inhibiting substance regulates gonadotropin gene expression PMID: 12878721
      7. MIS inhibits regeneration of Leydig cells in ethylene dimethanesulfonate-treated rats by enhancing apoptotic cell death as well as by decreasing proliferative capacity. PMID: 14585814

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    • 亚细胞定位:
      Secreted.
    • 蛋白家族:
      TGF-beta family
    • 数据库链接:


    1v1周青梅郑宣木天寥
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