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  • Your Good Partner in Biology Research

    KLRC3 Antibody

    Datasheet
    • 货号:
      CSB-PA23099A0Rb
    • 规格:
      ¥1320
    • 图片:
      • IHC image of CSB-PA23099A0Rb diluted at 1:400 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
      • Immunofluorescence staining of Hela cells with CSB-PA23099A0Rb at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • 其他:

    产品详情

    • 产品名称:
      Rabbit anti-Homo sapiens (Human) KLRC3 Polyclonal antibody
    • Uniprot No.:
    • 基因名:
      KLRC3
    • 别名:
      Killer cell lectin like receptor subfamily C member 3 antibody; KLRC 3 antibody; KLRC3 antibody; NK cell receptor E antibody; NKG2 E activating NK receptor antibody; NKG2 E antibody; NKG2 E type II integral membrane protein antibody; NKG2-E type II integral membrane protein antibody; NKG2-E-activating NK receptor antibody; NKG2E activating NK receptor antibody; NKG2E antibody; NKG2E type II integral membrane protein antibody; NKG2E_HUMAN antibody
    • 宿主:
      Rabbit
    • 反应种属:
      Human
    • 免疫原:
      Recombinant Human NKG2-E type II integral membrane protein (94-240AA)
    • 免疫原种属:
      Homo sapiens (Human)
    • 标记方式:
      Non-conjugated

      本页面中的产品,KLRC3 Antibody (CSB-PA23099A0Rb),的标记方式是Non-conjugated。对于KLRC3 Antibody,我们还提供其他标记。见下表:

      可提供标记
      标记方式 货号 产品名称 应用
      HRP CSB-PA23099B0Rb KLRC3 Antibody, HRP conjugated ELISA
      FITC CSB-PA23099C0Rb KLRC3 Antibody, FITC conjugated
      Biotin CSB-PA23099D0Rb KLRC3 Antibody, Biotin conjugated ELISA
    • 克隆类型:
      Polyclonal
    • 抗体亚型:
      IgG
    • 纯化方式:
      >95%, Protein G purified
    • 浓度:
      It differs from different batches. Please contact us to confirm it.
    • 保存缓冲液:
      Preservative: 0.03% Proclin 300
      Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
    • 产品提供形式:
      Liquid
    • 应用范围:
      ELISA, IHC, IF
    • 推荐稀释比:
      Application Recommended Dilution
      IHC 1:200-1:500
      IF 1:50-1:200
    • Protocols:
    • 储存条件:
      Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
    • 货期:
      Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

    产品评价

    靶点详情

    • 功能:
      Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
    • 基因功能参考文献:
      1. KLRC3 gene expression is linked to glioblastoma aggressiveness. PMID: 27641066
      2. Data indicate that NKG2 receptor NKG2E was capable of associating with CD94 and DAP12 but that the complex was retained intracellularly at the endoplasmic reticulum. PMID: 24935923
      3. Data indicate that the expression of KLRD1 (CD94) and NKG2E (KLRC3) was reduced in NK-enriched cells in fulminant type 1 diabetes. PMID: 24177169
    • 亚细胞定位:
      Membrane; Single-pass type II membrane protein.
    • 组织特异性:
      Natural killer cells.
    • 数据库链接:

      HGNC: 6376

      OMIM: 602892

      KEGG: hsa:3823

      STRING: 9606.ENSP00000437563

      UniGene: Hs.654362



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