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  • Your Good Partner in Biology Research

    Alb Antibody, Biotin conjugated

    Datasheet
    • 货号:
      CSB-PA00080H1Rb
    • 规格:
      ¥1320
    • 其他:

    产品详情

    • 产品名称:
      Rabbit anti-Mus musculus (Mouse) Alb Polyclonal antibody
    • Uniprot No.:
    • 基因名:
      Alb
    • 别名:
      Alb 1 antibody; alb antibody; ALBU_MOUSE antibody; Albumin 1 antibody; Albumin antibody; Serum albumin antibody
    • 宿主:
      Rabbit
    • 反应种属:
      Mouse
    • 免疫原:
      Serum Albumin purified from Mouse serum (Native Protein)
    • 免疫原种属:
      Mus musculus (Mouse)
    • 标记方式:
      Biotin
    • 克隆类型:
      Polyclonal
    • 抗体亚型:
      IgG
    • 纯化方式:
      >95%, Protein G purified
    • 浓度:
      It differs from different batches. Please contact us to confirm it.
    • 保存缓冲液:
      Preservative: 0.03% Proclin 300
      Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
    • 产品提供形式:
      Liquid
    • 应用范围:
      ELISA
    • Protocols:
    • 储存条件:
      Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
    • 货期:
      Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

    产品评价

    靶点详情

    • 功能:
      Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli. Does not prevent iron uptake by the bacterial siderophore aerobactin.
    • 基因功能参考文献:
      1. findings suggest that HMGB1 induces the transcytosis of albumin via RAGE-dependent Src phosphorylation and Cav-1 phosphorylation. These studies revealed a new mechanism of HMGB1-induced endothelial hyperpermeability. PMID: 27572515
      2. Urinary L-FABP, NGAL, Kim-1 and albumin levels increased during the acute phase of kidney injury and were significantly correlated with the degree of tubulointerstitial fibrosis during the chronic phase. These markers could detect higher risk of progression to CKD. PMID: 27028054
      3. Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding. PMID: 24652290
      4. We provide evidence of a transcytosis within the kidney tubular system that protects albumin and IgG from lysosomal degradation, allowing these proteins to be recycled intact. PMID: 23970123
      5. albumin may play a distinct role in adipocyte differentiation by promoting lipid accumulation. PMID: 20529675
      6. No binding of albumin was observed at physiological pH to neonatal Fc receptor. At acidic pH, a 100-fold difference in binding affinity was observed. PMID: 20018855
      7. Cellular oxidant stress and advanced glycation endproducts of albumin: caveats of the dichlorofluorescein assay PMID: 11913966
      8. albumin enhancer/promoter was succesfully used for trasient transfection of fluorescent gene reporters (for cell sorting) in ES spontaneously differentiated into hepatocytes. PMID: 18942772

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    • 亚细胞定位:
      Secreted.
    • 蛋白家族:
      ALB/AFP/VDB family
    • 组织特异性:
      Plasma. Expressed in the granular cells within the cerebellum.
    • 数据库链接:


    1v1周青梅郑宣木天寥
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